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The Mycobacterium tuberculosis GroEL1 Chaperone Is a Substrate of Ser/Thr Protein Kinases

We demonstrate that Mycobacterium tuberculosis GroEL1 is phosphorylated by PknF at two positions, Thr25 and Thr54. Unexpectedly, Mycobacterium smegmatis GroEL1 is not a substrate of its cognate PknF. This study shows that the phosphorylation profiles of conserved proteins are species dependent and p...

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Detalhes bibliográficos
Main Authors: Canova, Marc J., Kremer, Laurent, Molle, Virginie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668390/
https://ncbi.nlm.nih.gov/pubmed/19201798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01569-08
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