A novel cis-acting element from the 3′UTR of DNA damage-binding protein 2 mRNA links transcriptional and post-transcriptional regulation of gene expression

The DNA damage-binding protein 2 (DDB2) is an adapter protein that can direct a modular Cul4-DDB1-RING E3 Ligase complex to sites of ultraviolet light-induced DNA damage to ubiquitinate substrates during nucleotide excision repair. The DDB2 transcript is ultraviolet-inducible; therefore, its regulat...

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Hlavní autoři: Melanson, Brian D., Cabrita, Miguel A., Bose, Reetesh, Hamill, Jeffrey D., Pan, Elysia, Brochu, Christian, Marcellus, Kristen A., Zhao, Tong T., Holcik, Martin, McKay, Bruce C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Gene Regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675493/
https://ncbi.nlm.nih.gov/pubmed/23605047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt279
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