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Distinct 5′ UTRs regulate XIAP expression under normal growth conditions and during cellular stress

X-chromosome linked inhibitor of apoptosis, XIAP, is cellular caspase inhibitor and a key regulator of apoptosis. We and others have previously shown that XIAP expression is regulated primarily at the level of protein synthesis; the 5′ untranslated region (UTR) of XIAP mRNA contains an Internal Ribo...

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Detalhes bibliográficos
Main Authors: Riley, Alura, Jordan, Lindsay E., Holcik, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919726/
https://ncbi.nlm.nih.gov/pubmed/20385593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq241
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