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Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions

Cells respond to environmental stress by inducing translation of a subset of mRNAs important for survival or apoptosis. CHOP, a downstream transcriptional target of stress-induced ATF4, is also regulated translationally in a uORF-dependent manner under stress. Low concentration of anisomycin induces...

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Detalhes bibliográficos
Main Authors: Chen, Yi-Jiun, Tan, Bertrand Chin-Ming, Cheng, Ya-Yun, Chen, Jin-Shin, Lee, Sheng-Chung
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817461/
https://ncbi.nlm.nih.gov/pubmed/19934253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1034
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