Llwytho...

The role of mRNA decay in p53-induced gene expression

The p53 tumor suppressor is a DNA-damage-responsive sequence-specific transcriptional activator. The sustained activation of the p53 response is incompatible with cell growth and viability. To circumvent this issue, a variety of negative feedback loops exist to limit the duration of p53 activation....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Melanson, Brian D., Bose, Reetesh, Hamill, Jeff D., Marcellus, Kristen A., Pan, Elysia F., McKay, Bruce C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222134/
https://ncbi.nlm.nih.gov/pubmed/22020975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030122.111
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!