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The role of mRNA decay in p53-induced gene expression
The p53 tumor suppressor is a DNA-damage-responsive sequence-specific transcriptional activator. The sustained activation of the p53 response is incompatible with cell growth and viability. To circumvent this issue, a variety of negative feedback loops exist to limit the duration of p53 activation....
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Cold Spring Harbor Laboratory Press
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222134/ https://ncbi.nlm.nih.gov/pubmed/22020975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.030122.111 |
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