A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA

Transcription and mRNA export are linked processes. However, the molecular mechanisms of this coordination are not clear. Sus1 (hENY2) participates in this coordination as part of two protein complexes: SAGA, a transcriptional co-activator; TREX-2, which functions in mRNA biogenesis and export. Here...

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Main Authors: García-Oliver, Encar, Pascual-García, Pau, García-Molinero, Varinia, Lenstra, Tineke L., Holstege, Frank C. P., Rodríguez-Navarro, Susana
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Gene Regulation, Chromatin and Epigenetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675487/
https://ncbi.nlm.nih.gov/pubmed/23599000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt272
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