The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

BACKGROUND: Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recruited ge...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Epigenetics Chromatin
Prif Awduron: García-Molinero, Varinia, García-Martínez, José, Reja, Rohit, Furió-Tarí, Pedro, Antúnez, Oreto, Vinayachandran, Vinesh, Conesa, Ana, Pugh, B. Franklin, Pérez-Ortín, José E., Rodríguez-Navarro, Susana
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875001/
https://ncbi.nlm.nih.gov/pubmed/29598828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0184-2
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