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The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

BACKGROUND: Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recruited ge...

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Dettagli Bibliografici
Pubblicato in:Epigenetics Chromatin
Autori principali: García-Molinero, Varinia, García-Martínez, José, Reja, Rohit, Furió-Tarí, Pedro, Antúnez, Oreto, Vinayachandran, Vinesh, Conesa, Ana, Pugh, B. Franklin, Pérez-Ortín, José E., Rodríguez-Navarro, Susana
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875001/
https://ncbi.nlm.nih.gov/pubmed/29598828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0184-2
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