The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

BACKGROUND: Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recruited ge...

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Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: García-Molinero, Varinia, García-Martínez, José, Reja, Rohit, Furió-Tarí, Pedro, Antúnez, Oreto, Vinayachandran, Vinesh, Conesa, Ana, Pugh, B. Franklin, Pérez-Ortín, José E., Rodríguez-Navarro, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875001/
https://ncbi.nlm.nih.gov/pubmed/29598828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0184-2
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