The SAGA/TREX-2 subunit Sus1 binds widely to transcribed genes and affects mRNA turnover globally

Abstract Background Eukaryotic transcription is regulated through two complexes, the general transcription factor IID (TFIID) and the coactivator Spt–Ada–Gcn5 acetyltransferase (SAGA). Recent findings confirm that both TFIID and SAGA contribute to the synthesis of nearly all transcripts and are recr...

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Detalhes bibliográficos
Main Authors: Varinia García-Molinero, José García-Martínez, Rohit Reja, Pedro Furió-Tarí, Oreto Antúnez, Vinesh Vinayachandran, Ana Conesa, B. Franklin Pugh, José E. Pérez-Ortín, Susana Rodríguez-Navarro
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-03-01
Colecção:Epigenetics & Chromatin
Assuntos:
Sus1
SAGA
Transcription
GRO
ChIP-exo
Acesso em linha:http://link.springer.com/article/10.1186/s13072-018-0184-2
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