A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA

Transcription and mRNA export are linked processes. However, the molecular mechanisms of this coordination are not clear. Sus1 (hENY2) participates in this coordination as part of two protein complexes: SAGA, a transcriptional co-activator; TREX-2, which functions in mRNA biogenesis and export. Here...

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Bibliographic Details
Main Authors: García-Oliver, Encar, Pascual-García, Pau, García-Molinero, Varinia, Lenstra, Tineke L., Holstege, Frank C. P., Rodríguez-Navarro, Susana
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675487/
https://ncbi.nlm.nih.gov/pubmed/23599000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt272
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