A novel role for Sem1 and TREX-2 in transcription involves their impact on recruitment and H2B deubiquitylation activity of SAGA

Transcription and mRNA export are linked processes. However, the molecular mechanisms of this coordination are not clear. Sus1 (hENY2) participates in this coordination as part of two protein complexes: SAGA, a transcriptional co-activator; TREX-2, which functions in mRNA biogenesis and export. Here...

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Main Authors: García-Oliver, Encar, Pascual-García, Pau, García-Molinero, Varinia, Lenstra, Tineke L., Holstege, Frank C. P., Rodríguez-Navarro, Susana
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Gene Regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675487/
https://ncbi.nlm.nih.gov/pubmed/23599000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt272
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