High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases

Transcription activator-like effector nucleases (TALENs) are a powerful new approach for targeted gene disruption in various animal models, but little is known about their activities in Mus musculus, the widely used mammalian model organism. Here, we report that direct injection of in vitro transcri...

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Библиографические подробности
Главные авторы: Qiu, Zhongwei, Liu, Meizhen, Chen, Zhaohua, Shao, Yanjiao, Pan, Hongjie, Wei, Gaigai, Yu, Chao, Zhang, Long, Li, Xia, Wang, Ping, Fan, Heng-Yu, Du, Bing, Liu, Bin, Liu, Mingyao, Li, Dali
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2013
Предметы:
Methods Online
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675477/
https://ncbi.nlm.nih.gov/pubmed/23630316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt258
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