High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases

Transcription activator-like effector nucleases (TALENs) are a powerful new approach for targeted gene disruption in various animal models, but little is known about their activities in Mus musculus, the widely used mammalian model organism. Here, we report that direct injection of in vitro transcri...

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Detalhes bibliográficos
Main Authors: Qiu, Zhongwei, Liu, Meizhen, Chen, Zhaohua, Shao, Yanjiao, Pan, Hongjie, Wei, Gaigai, Yu, Chao, Zhang, Long, Li, Xia, Wang, Ping, Fan, Heng-Yu, Du, Bing, Liu, Bin, Liu, Mingyao, Li, Dali
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675477/
https://ncbi.nlm.nih.gov/pubmed/23630316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt258
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