High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases

Transcription activator-like effector nucleases (TALENs) are a powerful new approach for targeted gene disruption in various animal models, but little is known about their activities in Mus musculus, the widely used mammalian model organism. Here, we report that direct injection of in vitro transcri...

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Hlavní autoři: Qiu, Zhongwei, Liu, Meizhen, Chen, Zhaohua, Shao, Yanjiao, Pan, Hongjie, Wei, Gaigai, Yu, Chao, Zhang, Long, Li, Xia, Wang, Ping, Fan, Heng-Yu, Du, Bing, Liu, Bin, Liu, Mingyao, Li, Dali
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675477/
https://ncbi.nlm.nih.gov/pubmed/23630316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt258
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