Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos

The CRISPR-Cas RNA-guided system has versatile uses in many organisms and allows modification of multiple target sites simultaneously. Generating novel genetically modified mouse and rat models is one valuable application of this system. Through the injection of Cas9 protein instead of mRNA into emb...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Wang, Liren, Shao, Yanjiao, Guan, Yuting, Li, Liang, Wu, Lijuan, Chen, Fangrui, Liu, Meizhen, Chen, Huaqing, Ma, Yanlin, Ma, Xueyun, Liu, Mingyao, Li, Dali
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4664917/
https://ncbi.nlm.nih.gov/pubmed/26620761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17517
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia