Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver

Aberrant DNA methylation is a common feature of neoplastic lesions, and early detection of such changes may provide powerful mechanistic insights and biomarkers for carcinogenesis. Here, we investigate dynamic changes in the mouse liver DNA methylome associated with short (1 day) and prolonged (7, 2...

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Bibliografski detalji
Glavni autori: Thomson, John P., Hunter, Jennifer M., Lempiäinen, Harri, Müller, Arne, Terranova, Rémi, Moggs, Jonathan G., Meehan, Richard R.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Gene Regulation, Chromatin and Epigenetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675467/
https://ncbi.nlm.nih.gov/pubmed/23598998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt232
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