Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver

Aberrant DNA methylation is a common feature of neoplastic lesions, and early detection of such changes may provide powerful mechanistic insights and biomarkers for carcinogenesis. Here, we investigate dynamic changes in the mouse liver DNA methylome associated with short (1 day) and prolonged (7, 2...

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Detalhes bibliográficos
Main Authors: Thomson, John P., Hunter, Jennifer M., Lempiäinen, Harri, Müller, Arne, Terranova, Rémi, Moggs, Jonathan G., Meehan, Richard R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Gene Regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675467/
https://ncbi.nlm.nih.gov/pubmed/23598998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt232
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