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Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome
BACKGROUND: Induction and promotion of liver cancer by exposure to non-genotoxic carcinogens coincides with epigenetic perturbations, including specific changes in DNA methylation. Here we investigate the genome-wide dynamics of 5-hydroxymethylcytosine (5hmC) as a likely intermediate of 5-methylcyto...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491421/ https://ncbi.nlm.nih.gov/pubmed/23034186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-10-r93 |
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