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Detoxication Strategy of Epoxide Hydrolase—The Basis for a Novel Threshold for Definable Genotoxic Carcinogens

From our recent work on the three-dimensional structure of epoxide hydrolases we theoretically deduced the likelihood of a two-step catalytic mechanism that we and others have subsequently experimentally confirmed. Analysis of the rate of the two steps by us and by others show that the first step—re...

詳細記述

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書誌詳細
主要な著者: Franz Oesch, Jan Georg Hengstler, Michael Arand
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publishing 2004-01-01
シリーズ:Dose-Response
オンライン・アクセス:https://doi.org/10.1080/15401420490426963
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