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Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver
Aberrant DNA methylation is a common feature of neoplastic lesions, and early detection of such changes may provide powerful mechanistic insights and biomarkers for carcinogenesis. Here, we investigate dynamic changes in the mouse liver DNA methylome associated with short (1 day) and prolonged (7, 2...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3675467/ https://ncbi.nlm.nih.gov/pubmed/23598998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt232 |
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