Natural Killer Cells Generated from Cord Blood Hematopoietic Progenitor Cells Efficiently Target Bone Marrow-Residing Human Leukemia Cells in NOD/SCID/IL2Rg(null) Mice

Natural killer (NK) cell-based adoptive immunotherapy is an attractive adjuvant treatment option for patients with acute myeloid leukemia. Recently, we reported a clinical-grade, cytokine-based culture method for the generation of NK cells from umbilical cord blood (UCB) CD34(+) hematopoietic progen...

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Detalhes bibliográficos
Main Authors: Cany, Jeannette, van der Waart, Anniek B., Tordoir, Marleen, Franssen, Gerben M., Hangalapura, Basav N., de Vries, Jolanda, Boerman, Otto, Schaap, Nicolaas, van der Voort, Robbert, Spanholtz, Jan, Dolstra, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673996/
https://ncbi.nlm.nih.gov/pubmed/23755121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064384
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