Decitabine enhances targeting of AML cells by CD34(+) progenitor-derived NK cells in NOD/SCID/IL2Rg(null) mice

Combining natural killer (NK) cell adoptive transfer with hypomethylating agents (HMAs) is an attractive therapeutic approach for patients with acute myeloid leukemia (AML). However, data regarding the impact of HMAs on NK cell functionality are mostly derived from in vitro studies with high nonclin...

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Foilsithe in:Blood
Main Authors: Cany, Jeannette, Roeven, Mieke W. H., Hoogstad-van Evert, Janneke S., Hobo, Willemijn, Maas, Frans, Franco Fernandez, Rosalia, Blijlevens, Nicole M. A., van der Velden, Walter J., Huls, Gerwin, Jansen, Joop H., Schaap, Nicolaas P. M., Dolstra, Harry
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2018
Ábhair:
Immunobiology and Immunotherapy
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757681/
https://ncbi.nlm.nih.gov/pubmed/29138222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-790204
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