Umbilical cord blood CD34(+) progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rg(null) mice

Adoptive transfer of allogeneic natural killer (NK) cells is an attractive therapy approach against ovarian carcinoma. Here, we evaluated the potency of highly active NK cells derived from human CD34+ haematopoietic stem and progenitor cells (HSPC) to infiltrate and mediate killing of human ovarian...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Hoogstad-van Evert, Janneke S., Cany, Jeannette, van den Brand, Dirk, Oudenampsen, Manon, Brock, Roland, Torensma, Ruurd, Bekkers, Ruud L., Jansen, Joop H., Massuger, Leon F., Dolstra, Harry
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593716/
https://ncbi.nlm.nih.gov/pubmed/28919991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320630
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