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Umbilical cord blood CD34(+) progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rg(null) mice

Adoptive transfer of allogeneic natural killer (NK) cells is an attractive therapy approach against ovarian carcinoma. Here, we evaluated the potency of highly active NK cells derived from human CD34+ haematopoietic stem and progenitor cells (HSPC) to infiltrate and mediate killing of human ovarian...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Hoogstad-van Evert, Janneke S., Cany, Jeannette, van den Brand, Dirk, Oudenampsen, Manon, Brock, Roland, Torensma, Ruurd, Bekkers, Ruud L., Jansen, Joop H., Massuger, Leon F., Dolstra, Harry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593716/
https://ncbi.nlm.nih.gov/pubmed/28919991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320630
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