Umbilical cord blood CD34(+) progenitor-derived NK cells efficiently kill ovarian cancer spheroids and intraperitoneal tumors in NOD/SCID/IL2Rg(null) mice

Adoptive transfer of allogeneic natural killer (NK) cells is an attractive therapy approach against ovarian carcinoma. Here, we evaluated the potency of highly active NK cells derived from human CD34+ haematopoietic stem and progenitor cells (HSPC) to infiltrate and mediate killing of human ovarian...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Hoogstad-van Evert, Janneke S., Cany, Jeannette, van den Brand, Dirk, Oudenampsen, Manon, Brock, Roland, Torensma, Ruurd, Bekkers, Ruud L., Jansen, Joop H., Massuger, Leon F., Dolstra, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593716/
https://ncbi.nlm.nih.gov/pubmed/28919991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320630
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