Decitabine enhances targeting of AML cells by CD34(+) progenitor-derived NK cells in NOD/SCID/IL2Rg(null) mice

Combining natural killer (NK) cell adoptive transfer with hypomethylating agents (HMAs) is an attractive therapeutic approach for patients with acute myeloid leukemia (AML). However, data regarding the impact of HMAs on NK cell functionality are mostly derived from in vitro studies with high nonclin...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Cany, Jeannette, Roeven, Mieke W. H., Hoogstad-van Evert, Janneke S., Hobo, Willemijn, Maas, Frans, Franco Fernandez, Rosalia, Blijlevens, Nicole M. A., van der Velden, Walter J., Huls, Gerwin, Jansen, Joop H., Schaap, Nicolaas P. M., Dolstra, Harry
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2018
Matèries:
Immunobiology and Immunotherapy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757681/
https://ncbi.nlm.nih.gov/pubmed/29138222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-790204
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