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Augmented Pulmonary Responses to Acute Ozone Exposure in Obese Mice: Roles of TNFR2 and IL-13

Background: Acute ozone (O(3)) exposure results in greater inflammation and airway hyperresponsiveness (AHR) in obese versus lean mice. Objectives: We examined the hypothesis that these augmented responses to O(3) are the result of greater signaling through tumor necrosis factor receptor 2 (TNFR2) a...

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Autors principals: Williams, Alison Suzanne, Mathews, Joel Andrew, Kasahara, David Itiro, Chen, Lucas, Wurmbrand, Allison Patricia, Si, Huiqing, Shore, Stephanie Ann
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673194/
https://ncbi.nlm.nih.gov/pubmed/23434795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1205880
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