IL-33 Drives Augmented Responses to Ozone in Obese Mice

BACKGROUND: Ozone increases IL-33 in the lungs, and obesity augments the pulmonary effects of acute ozone exposure. OBJECTIVES: We assessed the role of IL-33 in the augmented effects of ozone observed in obese mice. METHODS: Lean wildtype and obese db/db mice were pretreated with antibodies blocking...

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Detalhes bibliográficos
Publicado no:Environ Health Perspect
Main Authors: Mathews, Joel A., Krishnamoorthy, Nandini, Kasahara, David Itiro, Cho, Youngji, Wurmbrand, Allison Patricia, Ribeiro, Luiza, Smith, Dirk, Umetsu, Dale, Levy, Bruce D., Shore, Stephanie Ann
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289908/
https://ncbi.nlm.nih.gov/pubmed/27472835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP272
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