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Innate and ozone-induced airway hyperresponsiveness in obese mice: role of TNF-α

Innate airway hyperresponsiveness (AHR) and augmented responses to ozone, an asthma trigger, are characteristics of obese mice. Systemic inflammation, a condition of increased circulating concentrations of inflammatory moieties, occurs in obesity. We hypothesized that TNF-α, via its effects as a mas...

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Publicat a:Am J Physiol Lung Cell Mol Physiol
Autors principals: Williams, Alison Suzanne, Mathews, Joel Andrew, Kasahara, David Itiro, Wurmbrand, Allison Patricia, Chen, Lucas, Shore, Stephanie Ann
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451401/
https://ncbi.nlm.nih.gov/pubmed/25840999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00393.2014
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