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Obesity and airway responsiveness: role of TNFR2

Obese mice exhibit innate airway hyperresponsiveness (AHR), a feature of asthma. Tumor necrosis factor alpha (TNFα) is implicated in the disease progression and chronic inflammatory status of both obesity and asthma. TNF acts via two TNF receptors, TNFR1 and TNFR2. To examine the role of TNFR2 in th...

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Detalhes bibliográficos
Main Authors: Williams, Alison S., Chen, Lucas, Kasahara, David I., Si, Huiqing, Wurmbrand, Allison P., Shore, Stephanie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440516/
https://ncbi.nlm.nih.gov/pubmed/22584291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pupt.2012.05.001
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