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ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice
Ozone causes airway hyperresponsiveness (AHR) and pulmonary inflammation. Rho kinase (ROCK) is a key regulator of smooth muscle cell contraction and inflammatory cell migration. To determine the contribution of the two ROCK isoforms ROCK1 and ROCK2 to ozone-induced AHR, we exposed wild-type, ROCK1(+...
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| Publicado no: | Am J Physiol Lung Cell Mol Physiol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4593838/ https://ncbi.nlm.nih.gov/pubmed/26276827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00372.2014 |
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