ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice

Ozone causes airway hyperresponsiveness (AHR) and pulmonary inflammation. Rho kinase (ROCK) is a key regulator of smooth muscle cell contraction and inflammatory cell migration. To determine the contribution of the two ROCK isoforms ROCK1 and ROCK2 to ozone-induced AHR, we exposed wild-type, ROCK1(+...

Full description

Saved in:
Bibliographic Details
Published in:Am J Physiol Lung Cell Mol Physiol
Main Authors: Kasahara, David I., Mathews, Joel A., Park, Chan Y., Cho, Youngji, Hunt, Gabrielle, Wurmbrand, Allison P., Liao, James K., Shore, Stephanie A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2015
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593838/
https://ncbi.nlm.nih.gov/pubmed/26276827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00372.2014
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items