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Abrogation of Airway Hyperresponsiveness but not Inflammation by Rho kinase Insufficiency
BACKGROUND: Major features of allergic asthma include airway hyperresponsiveness (AHR), eosinophilic inflammation, and goblet cell metaplasia. Rho kinase (ROCK) is a serine/threonine protein kinase that regulates the actin cytoskeleton. By doing so, it can modulate airway smooth muscle cell contract...
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| Publicado no: | Clin Exp Allergy |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4568824/ https://ncbi.nlm.nih.gov/pubmed/25323425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cea.12438 |
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