Augmented Responses to Ozone in Obese Mice Require IL-17A and Gastrin-Releasing Peptide

Ozone and obesity both increase IL-17A in the lungs. In mice, obesity augments the airway hyperresponsiveness and neutrophil recruitment induced by acute ozone exposure. Therefore, we examined the role of IL-17A in obesity-related increases in the response to ozone observed in obese mice. Lean wild-...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Mathews, Joel A., Krishnamoorthy, Nandini, Kasahara, David I., Hutchinson, John, Cho, Youngji, Brand, Jeffrey D., Williams, Alison S., Wurmbrand, Allison P., Ribeiro, Luiza, Cuttitta, Frank, Sunday, Mary E., Levy, Bruce D., Shore, Stephanie A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854955/
https://ncbi.nlm.nih.gov/pubmed/28957638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0071OC
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