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Integrating genealogical and dynamical modelling to infer escape and reversion rates in HIV epitopes
The rates of escape and reversion in response to selection pressure arising from the host immune system, notably the cytotoxic T-lymphocyte (CTL) response, are key factors determining the evolution of HIV. Existing methods for estimating these parameters from cross-sectional population data using or...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673055/ https://ncbi.nlm.nih.gov/pubmed/23677344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2013.0696 |
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