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Modelling the Evolution and Spread of HIV Immune Escape Mutants

During infection with human immunodeficiency virus (HIV), immune pressure from cytotoxic T-lymphocytes (CTLs) selects for viral mutants that confer escape from CTL recognition. These escape variants can be transmitted between individuals where, depending upon their cost to viral fitness and the CTL...

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Detalhes bibliográficos
Main Authors: Fryer, Helen R., Frater, John, Duda, Anna, Roberts, Mick G., Phillips, Rodney E., McLean, Angela R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987822/
https://ncbi.nlm.nih.gov/pubmed/21124991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001196
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