Modelling the Evolution and Spread of HIV Immune Escape Mutants

During infection with human immunodeficiency virus (HIV), immune pressure from cytotoxic T-lymphocytes (CTLs) selects for viral mutants that confer escape from CTL recognition. These escape variants can be transmitted between individuals where, depending upon their cost to viral fitness and the CTL...

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Bibliographic Details
Main Authors: Fryer, Helen R., Frater, John, Duda, Anna, Roberts, Mick G., Phillips, Rodney E., McLean, Angela R.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2987822/
https://ncbi.nlm.nih.gov/pubmed/21124991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001196
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