DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer

INTRODUCTION: Aberrant activation of Wnt/β-catenin signaling plays an important role in the pathogenesis of breast cancer. DACT1 (Dapper/Frodo) has been identified as involved in antagonizing Wnt/β-catenin signaling through interacting with Dishevelled (Dvl), a central mediator of Wnt signaling, whe...

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Autores principales: Yin, Xuedong, Xiang, Tingxiu, Li, LiLi, Su, Xianwei, Shu, Xingsheng, Luo, Xinrong, Huang, Jianbo, Yuan, Ying, Peng, Weiyan, Oberst, Michael, Kelly, Kathleen, Ren, Guosheng, Tao, Qian
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3672711/
https://ncbi.nlm.nih.gov/pubmed/23497530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3399
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