DACT2 silencing by promoter CpG methylation disrupts its regulation of epithelial-to-mesenchymal transition and cytoskeleton reorganization in breast cancer cells

Wnt signaling plays an important role in breast carcinogenesis. DAPPER2 (DACT2) functions as an inhibitor of canonical Wnt signaling and plays distinct roles in different cell contexts, with its role in breast tumorigenesis unclear. We investigated DACT2 expression in breast cancer cell lines and pr...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xiang, Tingxiu, Fan, Yichao, Li, Chunhong, Li, Lili, Ying, Ying, Mu, Junhao, Peng, Weiyan, Feng, Yixiao, Oberst, Michael, Kelly, Kathleen, Ren, Guosheng, Tao, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340116/
https://ncbi.nlm.nih.gov/pubmed/27708215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12341
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