Conformational templating of α-synuclein aggregates in neuronal-glial cultures

BACKGROUND: Genetic studies have established a causative role for α-synuclein (αS) in Parkinson’s disease (PD), and the presence of αS aggregates in the form of Lewy body (LB) and Lewy neurite (LN) protein inclusions are defining pathological features of PD. Recent data has established that extracel...

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Autores principales: Sacino, Amanda N, Thomas, Michael A, Ceballos-Diaz, Carolina, Cruz, Pedro E, Rosario, Awilda M, Lewis, Jada, Giasson, Benoit I, Golde, Todd E
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3671973/
https://ncbi.nlm.nih.gov/pubmed/23714769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-17
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