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Does a prion-like mechanism play a major role in the apparent spread of α-synuclein pathology?

Parkinson's disease, the most common movement disorder, results in an insidious reduction for patients in quality of life and ability to function. A hallmark of Parkinson's disease is the brain accumulation of neuronal cytoplasmic inclusions comprised of the protein α-synuclein. The presen...

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Detalhes bibliográficos
Main Authors: Sacino, Amanda N, Giasson, Benoit I
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3580457/
https://ncbi.nlm.nih.gov/pubmed/23245350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt151
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