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Prion-like spreading of pathological α-synuclein in brain
α-Synuclein is the major component of filamentous inclusions that constitute the defining characteristic of neurodegenerative α-synucleinopathies. However, the molecular mechanisms underlying α-synuclein accumulation and spread are unclear. Here we show that intracerebral injections of sarkosyl-inso...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3613715/ https://ncbi.nlm.nih.gov/pubmed/23466394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt037 |
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