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The Effect of Fragmented Pathogenic α-Synuclein Seeds on Prion-like Propagation

Aggregates of abnormal proteins are widely observed in neuronal and glial cells of patients with various neurodegenerative diseases, and it has been proposed that prion-like behavior of these proteins can account for not only the onset but also the progression of these diseases. However, it is not y...

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Vydáno v:J Biol Chem
Hlavní autoři: Tarutani, Airi, Suzuki, Genjiro, Shimozawa, Aki, Nonaka, Takashi, Akiyama, Haruhiko, Hisanaga, Shin-ichi, Hasegawa, Masato
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5009244/
https://ncbi.nlm.nih.gov/pubmed/27382062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.734707
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