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SENP3-mediated deSUMOylation of dynamin-related protein 1 promotes cell death following ischaemia
Global increases in small ubiquitin-like modifier (SUMO)-2/3 conjugation are a neuroprotective response to severe stress but the mechanisms and specific target proteins that determine cell survival have not been identified. Here, we demonstrate that the SUMO-2/3-specific protease SENP3 is degraded d...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
European Molecular Biology Organization
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3671254/ https://ncbi.nlm.nih.gov/pubmed/23524851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.65 |
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