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Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells

Over two decades have passed since the original discovery of amyloid precursor protein (APP). While physiological function(s) of APP still remain a matter of debate, consensus exists that the proteolytic processing of this protein represents a critical event in the life of neurons and that abnormali...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brunholz, Silke, Sisodia, Sangram, Lorenzo, Alfredo, Deyts, Carole, Kins, Stefan, Morfini, Gerardo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670699/
https://ncbi.nlm.nih.gov/pubmed/21960299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00221-011-2870-1
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