Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport

Alzheimer's β-amyloid precursor protein (APP) associates with kinesin-1 via JNK-interacting protein 1 (JIP1); however, the role of JIP1 in APP transport by kinesin-1 in neurons remains unclear. We performed a quantitative analysis to understand the role of JIP1 in APP axonal transport. In JIP1-...

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Publicado no:Mol Biol Cell
Main Authors: Chiba, Kyoko, Araseki, Masahiko, Nozawa, Keisuke, Furukori, Keiko, Araki, Yoichi, Matsushima, Takahide, Nakaya, Tadashi, Hata, Saori, Saito, Yuhki, Uchida, Seiichi, Okada, Yasushi, Nairn, Angus C., Davis, Roger J., Yamamoto, Tohru, Kinjo, Masataka, Taru, Hidenori, Suzuki, Toshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4230617/
https://ncbi.nlm.nih.gov/pubmed/25165140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-06-1111
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