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Phosphorylation of multiple sites within an acidic region of Alcadein α is required for kinesin-1 association and Golgi exit of Alcadein α cargo

Alcadein α (Alcα) is a major cargo of kinesin-1 that is subjected to anterograde transport in neuronal axons. Two tryptophan- and aspartic acid-containing (WD) motifs located in its cytoplasmic domain directly bind the tetratricopeptide repeat (TPR) motifs of the kinesin light chain (KLC), which act...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Sobu, Yuriko, Furukori, Keiko, Chiba, Kyoko, Nairn, Angus C., Kinjo, Masataka, Hata, Saori, Suzuki, Toshiharu
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739299/
https://ncbi.nlm.nih.gov/pubmed/29093024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-05-0301
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