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Retinal ganglion cell loss in kinesin-1 cargo Alcadein α deficient mice

Maintenance of retinal ganglion cells (RGCs) activity is relied on axonal transport conveying materials required for their survival such as neurotrophic factors. Kinesin-1 undergoes anterograde transport in axons, and Alcadein α (Alcα; also called calsyntenin-1) is a major cargo adaptor protein that...

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Vydáno v:Cell Death Dis
Hlavní autoři: Nakano, Yuki, Hirooka, Kazuyuki, Chiba, Yoichi, Ueno, Masaki, Ojima, Daiki, Hossain, Md Razib, Takahashi, Hiroo, Yamamoto, Tohru, Kiuchi, Yoshiaki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7054276/
https://ncbi.nlm.nih.gov/pubmed/32127528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2363-x
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