Nalaganje...
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport
Alcadeinα (Alcα) is an evolutionarily conserved type I membrane protein expressed in neurons. We show here that Alcα strongly associates with kinesin light chain (K(D)≈4–8 × 10(−9) M) through a novel tryptophan- and aspartic acid-containing sequence. Alcα can induce kinesin-1 association with vesicl...
Shranjeno v:
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2007
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1829376/ https://ncbi.nlm.nih.gov/pubmed/17332754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601609 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|