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Axonal transport of APP and the spatial regulation of APP cleavage and function in neuronal cells

Over two decades have passed since the original discovery of amyloid precursor protein (APP). While physiological function(s) of APP still remain a matter of debate, consensus exists that the proteolytic processing of this protein represents a critical event in the life of neurons and that abnormali...

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Hlavní autoři: Brunholz, Silke, Sisodia, Sangram, Lorenzo, Alfredo, Deyts, Carole, Kins, Stefan, Morfini, Gerardo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670699/
https://ncbi.nlm.nih.gov/pubmed/21960299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00221-011-2870-1
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