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APP Anterograde Transport Requires Rab3A GTPase Activity for Assembly of the Transport Vesicle
The amyloid precursor protein (APP) is anterogradely transported by conventional kinesin in a distinct transport vesicle, but both the biochemical composition of such a vesicle and the specific kinesin-1 motor responsible for transport are poorly defined. APP may be sequentially cleaved by β- and γ-...
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2849269/ https://ncbi.nlm.nih.gov/pubmed/19923287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1546-09.2009 |
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